Browse All Peptides

Every peptide graded A through D for evidence strength. Search, filter, and compare — with every claim backed by PubMed citations.

57
Peptides
22
FDA-Approved
9
Categories
35+
Comparisons

Understanding Evidence Grades

A

FDA-approved with robust clinical evidence

B

Supported by human clinical studies

C

Preclinical evidence only

D

Very limited or no published evidence

Search
Evidence Level
FDA Status
Category

Showing 57 of 57 peptides

BPC-157

C
Healing & Recovery

BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. Preclinical research suggests it may...

Not Approved

TB-500 (Thymosin Beta-4)

C
Healing & Recovery

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4. It plays a role in cell migration, blood vessel formation,...

Not Approved

GHK-Cu

B
Healing & Recovery

GHK-Cu (copper peptide, GHK copper) is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. Found in human pla...

Cosmetic

Ipamorelin

B
Growth Hormone Secretagogues

Ipamorelin is a selective growth hormone secretagogue that stimulates growth hormone release from the pituitary gland without significantly ...

Not Approved

CJC-1295

B
Growth Hormone Secretagogues

CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH). Available in two forms: with and without Drug Affinity Complex (D...

Not Approved

Sermorelin

A
Growth Hormone Secretagogues

Sermorelin is the shortest fully functional fragment of GHRH (amino acids 1-29). It was the first GHRH analog approved by the FDA, marketed ...

FDA Approved

Tesamorelin

A
Growth Hormone Secretagogues

Tesamorelin is a synthetic GHRH analog approved by the FDA as Egrifta for reduction of excess abdominal fat in HIV-infected patients with li...

FDA Approved

Bremelanotide (PT-141)

A
Sexual Health

Bremelanotide is a cyclic heptapeptide melanocortin receptor agonist approved by the FDA as Vyleesi for treatment of hypoactive sexual desir...

FDA Approved

Semaglutide

A
Weight Loss

Semaglutide is a GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Ozempic, Rybelsus) and chronic weight management (Wegovy). ...

FDA Approved

Tirzepatide

A
Weight Loss

Tirzepatide is the first dual GIP and GLP-1 receptor agonist, approved by the FDA for type 2 diabetes (Mounjaro) and chronic weight manageme...

FDA Approved

AOD-9604

C
Weight Loss

AOD-9604 is a modified fragment of human growth hormone (amino acids 176-191) originally developed for obesity treatment. It has been explor...

Not Approved

DSIP (Delta Sleep-Inducing Peptide)

D
Sleep & Stress

DSIP is a neuropeptide originally isolated from rabbit brain during induced sleep. Research suggests it may modulate sleep patterns, stress ...

Not Approved

Epithalon (Epitalon)

C
Anti-Aging & Longevity

Epithalon (also spelled Epitalon or Epitalone) is a synthetic tetrapeptide based on the natural peptide epithalamin, produced by the pineal ...

Not Approved

Selank

B
Sleep & Stress

Selank is a synthetic peptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is approved in Russia ...

Not Approved

Semax

B
Cognitive Enhancement

Semax is a synthetic peptide derived from the ACTH(4-10) fragment, developed in Russia as a nootropic and neuroprotective agent. It is appro...

Not Approved

GHRP-2

B
Growth Hormone Secretagogues

GHRP-2 is a synthetic hexapeptide growth hormone secretagogue. It is one of the most potent GHRPs and has been used in clinical research for...

Not Approved

GHRP-6

B
Growth Hormone Secretagogues

GHRP-6 was one of the first synthetic GH secretagogues developed. It stimulates strong GH release but also significantly increases appetite ...

Not Approved

Hexarelin

B
Growth Hormone Secretagogues

Hexarelin is one of the most potent synthetic GH secretagogues. Research also suggests it has direct cardioprotective effects independent of...

Not Approved

Melanotan II

C
Sexual Health

Melanotan II (also written as Melanotan 2, MT-2, or MT2) is a synthetic cyclic peptide analog of alpha-melanocyte stimulating hormone (alpha...

Not Approved

LL-37

C
Immune Support

LL-37 (also written as ll37 or ll-37) is the only cathelicidin antimicrobial peptide found in humans. It plays a crucial role in innate immu...

Not Approved

Thymalin

C
Immune Support

Thymalin is a synthetic dipeptide (glutamyl-tryptophan) originally derived from calf thymus extract. Developed by Vladimir Khavinson in Russ...

Not Approved

KPV

D
Anti-Inflammatory

KPV is a tripeptide derived from the C-terminal sequence of alpha-melanocyte stimulating hormone (alpha-MSH). Research suggests potent anti-...

Not Approved

Liraglutide

A
Weight Loss

Liraglutide is a GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Victoza) and chronic weight management (Saxenda). It was th...

FDA Approved

Retatrutide

B
Weight Loss

Retatrutide is an investigational triple-hormone receptor agonist developed by Eli Lilly. It simultaneously targets GIP, GLP-1, and glucagon...

Not Approved

Exenatide

A
Weight Loss

Exenatide is a GLP-1 receptor agonist and the first incretin mimetic approved by the FDA for type 2 diabetes (Byetta, 2005; Bydureon BCise, ...

FDA Approved

Dulaglutide

A
Weight Loss

Dulaglutide is a once-weekly GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Trulicity, 2014). It is a fusion protein consis...

FDA Approved

Teriparatide

A
Healing & Recovery

Teriparatide is a recombinant human parathyroid hormone analog (PTH 1-34) and the first anabolic (bone-building) agent approved by the FDA f...

FDA Approved

Octreotide

A
Immune Support

Octreotide is a synthetic cyclic octapeptide analog of somatostatin, approved by the FDA for acromegaly, carcinoid tumors, and vasoactive in...

FDA Approved

Triptorelin

A
Sexual Health

Triptorelin is a synthetic decapeptide agonist of gonadotropin-releasing hormone (GnRH), approved by the FDA for advanced prostate cancer, c...

FDA Approved

Desmopressin

A
Sleep & Stress

Desmopressin is a synthetic analog of arginine vasopressin (antidiuretic hormone) with enhanced V2 receptor selectivity and prolonged durati...

FDA Approved

Setmelanotide

A
Weight Loss

Setmelanotide is the first melanocortin-4 receptor (MC4R) agonist approved by the FDA for chronic weight management in patients with rare ge...

FDA Approved

Pramlintide

A
Weight Loss

Pramlintide is a synthetic analog of human amylin, a pancreatic beta-cell hormone co-secreted with insulin. It was approved by the FDA in 20...

Discontinued

Survodutide

B
Weight Loss

Survodutide is a dual GLP-1 and glucagon receptor agonist developed by Boehringer Ingelheim. In Phase 3 trials, it demonstrates significant ...

Not Approved

Linaclotide

A
Anti-Inflammatory

Linaclotide is a guanylate cyclase-C (GC-C) receptor agonist approved by the FDA for irritable bowel syndrome with constipation (IBS-C) and ...

FDA Approved

Plecanatide

A
Anti-Inflammatory

Plecanatide is a GC-C receptor agonist approved by the FDA for chronic idiopathic constipation (CIC) and irritable bowel syndrome with const...

FDA Approved

Teduglutide

A
Healing & Recovery

Teduglutide is a recombinant analog of human GLP-2 and the first FDA-approved therapy for short bowel syndrome (SBS) dependent on parenteral...

FDA Approved

Abaloparatide

A
Healing & Recovery

Abaloparatide is a synthetic analog of parathyroid hormone-related protein (PTHrP 1-34) approved by the FDA for osteoporosis in postmenopaus...

FDA Approved

Lanreotide

A
Immune Support

Lanreotide is a synthetic somatostatin analog approved by the FDA for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and acromegaly...

FDA Approved

Ziconotide

A
Sleep & Stress

Ziconotide is a synthetic peptide analog of omega-conotoxin MVIIA, derived from the venom of the cone snail Conus magus. It is the first non...

FDA Approved

Vosoritide

A
Healing & Recovery

Vosoritide is a recombinant analog of C-type natriuretic peptide (CNP) approved by the FDA for achondroplasia in children aged 5 years and o...

FDA Approved

SS-31 (Elamipretide)

B
Anti-Aging & Longevity

Elamipretide (SS-31) is a first-in-class mitochondria-targeted tetrapeptide that binds to cardiolipin in the inner mitochondrial membrane. I...

Not Approved

MOTS-c

C
Anti-Aging & Longevity

MOTS-c is a mitochondrial-derived peptide (MDP) encoded by the mitochondrial 16S rRNA gene. Discovered in 2015, it is an exercise-mimetic pe...

Not Approved

Humanin

C
Anti-Aging & Longevity

Humanin is the first discovered mitochondrial-derived peptide (MDP), identified in 2001 as a secreted factor that protects neurons from Alzh...

Not Approved

FOXO4-DRI

D
Anti-Aging & Longevity

FOXO4-DRI is a synthetic retro-inverso peptide designed to disrupt the FOXO4-p53 interaction, selectively inducing apoptosis in senescent ce...

Not Approved

Cerebrolysin

B
Cognitive Enhancement

Cerebrolysin is a parenteral neuropeptide preparation produced from purified porcine brain proteins. It contains a mixture of low-molecular-...

Not Approved

Oxytocin

A
Sleep & Stress

Oxytocin is a naturally occurring nonapeptide hormone produced in the hypothalamus and released by the posterior pituitary. Best known for i...

FDA Approved

Dihexa

D
Cognitive Enhancement

Dihexa is a synthetic heptapeptide analog of angiotensin IV, developed at Washington State University for potential treatment of Alzheimer's...

Not Approved

IGF-1 LR3

D
Growth Hormone Secretagogues

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a synthetic analog of human IGF-1 with an arginine substitution at position 3 and a 13-a...

Not Approved

Follistatin-344

D
Growth Hormone Secretagogues

Follistatin-344 is the full-length human follistatin isoform that binds and inhibits myostatin, activin, and other TGF-beta family members. ...

Not Approved

MGF (Mechano Growth Factor)

D
Growth Hormone Secretagogues

Mechano Growth Factor (MGF) is a splice variant of IGF-1 (specifically IGF-1Ec) that is upregulated in response to mechanical stress and mus...

Not Approved

P21

D
Cognitive Enhancement

P21 is a synthetic peptide derived from ciliary neurotrophic factor (CNTF), a cytokine with neurotrophic and neuroprotective properties. Dev...

Not Approved

Kisspeptin-10

B
Sexual Health & Fertility

Kisspeptin-10 is the minimal active fragment of kisspeptin (metastin), the endogenous ligand for the KISS1 receptor (GPR54). It is a potent ...

Not Approved

Gonadorelin (GnRH)

A
Sexual Health & Fertility

Gonadorelin is the synthetic form of gonadotropin-releasing hormone (GnRH), identical in structure to the endogenous decapeptide produced in...

FDA Approved

ARA-290 (Cibinetide)

B
Healing & Recovery

ARA-290 (cibinetide) is a peptide engineered from the structure of erythropoietin (EPO) that selectively activates the Innate Repair Recepto...

Not Approved

Adamax

D
Cognitive Enhancement

Adamax is a modified, more lipophilic analog of Semax in which the N-terminal acetyl group is replaced with an adamantane moiety. Semax itse...

Not Approved

Pinealon

C
Anti-Aging & Longevity

Pinealon (Glu-Asp-Arg) is a short tripeptide bioregulator developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Biore...

Not Approved

Tesofensine

A
Weight Loss & Metabolism

Tesofensine is a triple monoamine reuptake inhibitor (noradrenaline, dopamine, serotonin) originally developed for Parkinson's and Alzheimer...

Not Approved