Content reviewed by clinical research staff
Evidence graded using the PeptideScholar A-D system.
Hexarelin is one of the most potent synthetic GH secretagogues. Research also suggests it has direct cardioprotective effects independent of its GH-releasing properties.
Activates GHS receptors for GH release. Uniquely, also binds CD36 scavenger receptors in cardiac tissue, providing direct cardioprotective effects independent of GH signaling.
This content is for informational purposes only and does not constitute medical advice.
The dosing information above is sourced from published research literature and clinical trials. These are not recommendations. Individual responses vary. Always consult a healthcare provider before considering any peptide-based therapy.
Hexarelin is not FDA-approved. Always consult a licensed healthcare provider before considering any peptide.
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Endocrine, 2001
Hexarelin protected H9c2 cardiomyocytes from doxorubicin-induced cell death in vitro, suggesting direct cardioprotective properties independent of GH release
Int Heart J, 2017
Hexarelin binds cardiac CD36 receptors, protecting against ischemia-reperfusion injury independent of GH release
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This content is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendations.
Always consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Do not disregard professional medical advice based on information found on this site.
No claims of therapeutic efficacy are made for substances that are not FDA-approved for the discussed indications. Research citations reflect published findings and do not imply endorsement.