Last reviewed: March 2026Sources: PubMed, FDA, WADA Prohibited List
Evidence graded using the PeptideScholar A-D system.
CJC-1295
GHRH analog29 amino acids
BHuman Studies
80
Good Credibility
2 cited studies | Evidence level B
Not FDA ApprovedPrescription RequiredWADA Banned
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH). Available in two forms: with and without Drug Affinity Complex (DAC), which extends its half-life.
Mechanism of Action
Binds to GHRH receptors on pituitary somatotrophs, stimulating pulsatile growth hormone release. The DAC modification enables albumin binding, extending half-life to 6-8 days.
Not medical advice - research-reported information only
This content is for informational purposes only and does not constitute medical advice.
CJC-1295 - Dosing in Published Research
Reported routes: Subcutaneous injection
Clinical trial used single SC doses of 30-60 mcg/kg. CJC-1295 without DAC (Mod GRF 1-29) is dosed more frequently.
The dosing information above is sourced from published research literature and clinical trials. These are not recommendations. Individual responses vary. Always consult a healthcare provider before considering any peptide-based therapy.
1.Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.. J Clin Endocrinol Metab, 2006. "Single SC dose produced sustained 2-10 fold GH increases lasting 6+ days with IGF-1 elevation for 9-11 days" [PMID: 16352683]
2.Advances in the detection of growth hormone releasing hormone synthetic analogs.. Drug Test Anal, 2021. "Review of analytical methods for detecting GHRH synthetic analogs including CJC-1295 in anti-doping testing" [PMID: 34665524]
Recommended Resources
The Peptide Protocols Handbook
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Medical Disclaimer
This content is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendations.
Always consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Do not disregard professional medical advice based on information found on this site.
No claims of therapeutic efficacy are made for substances that are not FDA-approved for the discussed indications. Research citations reflect published findings and do not imply endorsement.