GHRP-2

BHuman Studies

Growth hormone releasing peptide · 6 amino acids

Not FDA ApprovedPrescription RequiredWADA Banned

GHRP-2 is a synthetic hexapeptide growth hormone secretagogue. It is one of the most potent GHRPs and has been used in clinical research for GH deficiency diagnosis.

Mechanism of Action

Binds ghrelin/GHS receptors in the pituitary and hypothalamus, stimulating GH release. Also stimulates appetite and increases cortisol and prolactin (less selective than ipamorelin).

Benefits

Potent GH release in human subjects
Used diagnostically for GH deficiency assessment
Increases appetite and food intake
Improved sleep quality in some studies

Not Medical Advice — Research-Reported Information Only

This content is for informational purposes only and does not constitute medical advice.

GHRP-2 — Dosing in Published Research

Reported Routes: Subcutaneous injection, Intravenous

Clinical studies used 1-2 mcg/kg IV or SC. Typically dosed 2-3 times daily in research protocols.

The dosing information above is sourced from published research literature and clinical trials. These are not recommendations. Individual responses vary. Always consult a healthcare provider before considering any peptide-based therapy.

Side Effects

Increased appetite and hunger
Elevated cortisol levels
Elevated prolactin levels
Water retention
Flushing

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Research & Evidence

RCTJournal of Clinical Endocrinology & Metabolism, 1997

GHRP-2 in the assessment of GH secretion

GHRP-2 was a potent and reliable GH secretagogue useful for diagnostic testing of GH reserve

PMID: 9089832

RCTEuropean Journal of Endocrinology, 1999

Combined use of GHRH and GHRP-2

GHRH + GHRP-2 combination produced synergistic GH release exceeding either agent alone

PMID: 10599720

Compare GHRP-2 With

References

1. GHRP-2 in the assessment of GH secretion. Journal of Clinical Endocrinology & Metabolism, 1997. “GHRP-2 was a potent and reliable GH secretagogue useful for diagnostic testing of GH reserve” [PMID: 9089832]
2. Combined use of GHRH and GHRP-2. European Journal of Endocrinology, 1999. “GHRH + GHRP-2 combination produced synergistic GH release exceeding either agent alone” [PMID: 10599720]

Recommended Resources

The Peptide Protocols Handbook

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Third-Party Peptide Testing

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Medical Disclaimer

This content is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendations.

Always consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Do not disregard professional medical advice based on information found on this site.

No claims of therapeutic efficacy are made for substances that are not FDA-approved for the discussed indications. Research citations reflect published findings and do not imply endorsement.