Selank vs Semax: Head-to-Head Comparison
Selank and Semax are both Russian-developed regulatory peptides approved in Russia for clinical use. Selank is an anxiolytic based on tuftsin (an immune peptide), while Semax is a nootropic based on ACTH(4-10). Selank targets anxiety and stress; Semax targets cognition and neuroprotection.
Side-by-Side Comparison
| Dimension | Selank | Semax |
|---|---|---|
| Evidence Level | Approved in Russia; multiple Russian clinical studies | Approved in Russia; extensive Russian clinical and preclinical data |
| FDA Status | Not approved in US/EU | Not approved in US/EU |
| Mechanism | GABA modulation, serotonin metabolism, immune modulation (tuftsin analog) | BDNF upregulation, dopamine/serotonin modulation (ACTH fragment) |
| Primary Use | Anxiety, stress, immune support | Cognitive enhancement, stroke recovery, neuroprotection |
| Side Effects | Very well-tolerated; mild fatigue possible | Well-tolerated; mild irritation with nasal use |
| Route of Administration | Intranasal drops | Intranasal drops |
| Onset | Anxiolytic effects within minutes to hours | Cognitive effects noticeable within hours |
Peptide Overviews
Selank
BHuman StudiesSelank is a synthetic peptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is approved in Russia as an anxiolytic and nootropic medication.
Semax
BHuman StudiesSemax is a synthetic peptide derived from the ACTH(4-10) fragment, developed in Russia as a nootropic and neuroprotective agent. It is approved in Russia for stroke, cognitive disorders, and optic nerve disease.
Selank vs Semax: FAQ
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