AnimalPMID: 26924987
Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.
Front Pharmacol, 2016
Selank modulated GABA neurotransmission gene expression, supporting anxiolytic mechanism of action
Content reviewed by clinical research staff
Evidence graded using the PeptideScholar A-D system.
Selank
BHuman Studies
80
Good Credibility
Not FDA ApprovedWADA Banned
Selank is a synthetic peptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is approved in Russia as an anxiolytic and nootropic medication.
Mechanism of Action
Modulates GABA and serotonin neurotransmission. Inhibits enkephalin-degrading enzymes, increasing endogenous enkephalin levels. Enhances BDNF expression.
Benefits
This content is for informational purposes only and does not constitute medical advice.
Selank - Dosing in Published Research
Reported routes: Intranasal, Subcutaneous injection
Russian approved dosing: 150-300 mcg intranasal 3 times daily for up to 14 days. Not FDA approved.
The dosing information above is sourced from published research literature and clinical trials. These are not recommendations. Individual responses vary. Always consult a healthcare provider before considering any peptide-based therapy.
Side Effects
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Research & Evidence
[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia].
Zh Nevrol Psikhiatr Im S S Korsakova, 2008
Selank showed anxiolytic activity comparable to benzodiazepines without sedation or muscle relaxation in clinical trials
Compare Selank With
References
- 1.Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.. Front Pharmacol, 2016. "Selank modulated GABA neurotransmission gene expression, supporting anxiolytic mechanism of action" [PMID: 26924987]
- 2.[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia].. Zh Nevrol Psikhiatr Im S S Korsakova, 2008. "Selank showed anxiolytic activity comparable to benzodiazepines without sedation or muscle relaxation in clinical trials" [PMID: 18454096]
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Selank FAQ
Medical Disclaimer
This content is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendations.
Always consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Do not disregard professional medical advice based on information found on this site.
No claims of therapeutic efficacy are made for substances that are not FDA-approved for the discussed indications. Research citations reflect published findings and do not imply endorsement.