Side Effect Probability Visualizer
Compare side effect rates for GLP-1 medications against placebo, sourced directly from FDA clinical trial data. Select one or more medications to compare.
Select medications to compare (select one or more):
Wegovy
Semaglutide 2.4mg · STEP 1-3 (pooled)
Discontinuation — Drug
6.8%
Discontinuation — Placebo
3.2%
% of participants who discontinued due to adverse events in each arm.
About This Data
All percentages are derived from the adverse event tables in each medication's FDA prescribing information, which in turn reflect pooled data from pivotal Phase 3 clinical trials. Side effects shown are those occurring in ≥3% of participants and at a higher rate than placebo.
Drug % is the percentage of participants in the active treatment arm who reported the side effect. Placebo % is the percentage in the placebo arm. The difference represents the attributable rate — how much the medication likely adds beyond baseline.
Discontinuation rate reflects the percentage of participants who stopped the medication due to adverse events in each arm of the trial. A higher discontinuation rate with drug vs placebo reflects medication tolerability.
Individual experience varies. These are population-level statistics from controlled trial conditions and may not reflect real-world use, especially with dose modifications.
Medical Disclaimer
This content is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendations.
Always consult a qualified healthcare provider before starting, stopping, or modifying any treatment. Do not disregard professional medical advice based on information found on this site.
No claims of therapeutic efficacy are made for substances that are not FDA-approved for the discussed indications. Research citations reflect published findings and do not imply endorsement.