Peptide Benchmark System
An evidence-based scoring system for peptides, providers, and stacks across multiple dimensions. Scores are calculated from FDA status, clinical trial data, cost, safety profiles, and practical factors. Use this to compare options objectively — not as a substitute for medical advice.
Preserves HPT axis and fertility. Phase I-II data in men. Not FDA-approved. Mechanism well-understood.
Russian clinical data for cognitive impairment. Not FDA-approved. Nasal route is convenient. Limited Western trials.
FDA-approved for obesity and T2DM. Strongest evidence base among all peptides. Expensive without insurance.
Russian data for anxiety. Not FDA-approved. Favorable safety. Mechanism poorly understood in Western literature.
FDA-approved. Superior weight loss vs semaglutide in head-to-head trial. Less cardiovascular outcome data.
Strong topical evidence for skin aging. Injectable human RCTs lacking. Naturally occurring, favorable safety.
FDA-approved for female HSDD (Vyleesi). Male ED data exists but not approved. ~40% nausea rate.
IV-only (inconvenient). Strong vascular dementia evidence. Not FDA-approved. Requires infusion center.
Telomerase activation claims. Small Russian studies. No replication in Western literature. Highly speculative.
Formerly FDA-approved for pediatric GH deficiency (discontinued). Good safety data. WADA-banned despite approval.
Mitochondrial-derived peptide. Animal data for metabolic health. No human RCTs. Emerging research area.
Cleanest GHRP profile — minimal cortisol/prolactin elevation. Phase I-II data. WADA-banned. No body comp RCTs.
FDA-approved for HIV lipodystrophy only. Strong evidence in that population. Expensive. WADA-banned.
Pharmacokinetic data exists. No RCTs for body composition in healthy adults. WADA-banned. Elevates IGF-1.
200+ animal studies, zero published human RCTs. WADA-banned. Mechanism unclear. Quality control concerns.
Thymosin Beta-4 fragment. Animal data only. WADA-banned. No human efficacy data.
Scoring Methodology
Overall scores are unweighted averages of all dimensions unless otherwise noted. You can adjust weights in the scoring API to prioritize dimensions that matter most to your use case.