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Bremelanotide (PT-141) Cost Guide: Insurance, Cash Pay, and Savings
In the United States, Bremelanotide (PT-141) costs depend on brand, pharmacy, insurance design, and whether the patient qualifies for manufacturer savings programs.
Active Market
This page is designed for US treatment decisions and uses US-first pricing and savings sources.
Official pricing
Verify current pricing directly on official Vyleesi pages before starting, because list pricing, self-pay offers, and eligibility terms can change.
Cash-pay reality
Official cash-pay pricing varies by pharmacy and dose. Contact multiple pharmacies or use a prescription discount service for current rates.
Insurance coverage
Commercial coverage for Bremelanotide (PT-141) varies by plan and indication. Prior authorization is commonly required.
Savings and coupons
Manufacturer savings programs may reduce out-of-pocket cost for eligible commercially insured patients.
Prior Authorization
Prior authorization is common and may require documentation of diagnosis, prior treatments, and clinical need.
Price Breakdown
List price (monthly)
~$900-$1,200/month (4-8 doses)
Average wholesale price
~$850-$1,100/month
Pharmacy acquisition estimate
~$800-$1,000/month
Typical negotiated rate
~$600-$850/month
Price per dose
~$113-$150 per 1.75 mg dose
Annual cost at list price
~$10,800-$14,400
Pharmacy Price Comparison
| Pharmacy | Price Range | Notes |
|---|---|---|
| Retail | $850-$1,200/month | Cash price |
| Specialty pharmacy | $800-$1,100/month | May offer better pricing |
Insurance Coverage Landscape
Commercial plans
~30-40% for HSDD; many plans exclude sexual dysfunction
Medicare Part D
Rarely covered
Medicaid
Rarely covered
VA coverage
Case-by-case
TRICARE
Limited
Employer plan typical tier
Tier 3-4 if covered; often excluded entirely
Prior Authorization Guide
Required Documentation
- •HSDD diagnosis (acquired, generalized)
- •Premenopausal status
- •Failed counseling/therapy
- •Flibanserin trial (sometimes required)
Common Denial Reasons
- •Plan excludes sexual dysfunction drugs
- •Postmenopausal (not approved)
- •Insufficient documentation
- •Lifestyle factors not addressed
Appeal Template Points
- •FDA-approved for acquired HSDD
- •Premenopausal status confirmed
- •Psychological intervention documented
- •Medical condition affecting quality of life
Expected timeline: 1-2 weeks
Savings Programs and Patient Assistance
Vyleesi Savings Card
copayEligibility: Commercially insured
Savings: $0-$99/month
Income limit: None
Enrollment: simple
AMAG/Palatin program
Patient Assistance
manufacturerEligibility: Uninsured, ≤400% FPL
Savings: Free or reduced
Income limit: ≤400% FPL
Enrollment: moderate
Limited availability
Generic and Biosimilar Status
No generic currently available
Expected: No generic expected soon
Cost by Dose
| Dose/Regimen | Monthly | Annual |
|---|---|---|
| 1.75 mg as needed (4 doses/month) | $900 | $10,800 |
| 1.75 mg as needed (8 doses/month) | $1,200 | $14,400 |
Annual Cost Projection
Year 1
$0-$14,400
Year 2
$0-$14,400
Year 3
$0-$14,400
Assumptions
- •As-needed dosing
- •Insurance variable
Cost-Saving Strategies
- 1.Start with 4 doses/month to assess response before increasing
- 2.Vyleesi savings card for commercially insured
- 3.Check if employer plan has any sexual dysfunction coverage
- 4.Document all prior interventions for prior auth
International Price Comparison
| Country | Price Range | Notes |
|---|---|---|
| UK | Limited availability | Not widely marketed |
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Reviewed 2026-04-27 by PeptideScholar editorial review. This page currently cites 3 official sources.
Pricing, savings eligibility, and coverage rules can change quickly. Verify all current figures and terms directly on official brand pages before acting.
Bremelanotide (PT-141) Cost FAQ
Sources
- 1. Prespecified and Integrated Subgroup Analyses from the RECONNECT Phase 3 Studies of Bremelanotide.J Womens Health (Larchmt) • 2022Claim type: clinicalView source →
- 2. Bremelanotide: First Approval.Drugs • 2019Claim type: reviewView source →
- 3. FDA Information on Bremelanotide (PT-141)FDA • 2026Claim type: regulatoryView source →
This content is for informational purposes only and does not constitute medical advice.