Structured page family:Cost guide

Bremelanotide (PT-141) Cost Guide: Insurance, Cash Pay, and Savings

In the United States, Bremelanotide (PT-141) costs depend on brand, pharmacy, insurance design, and whether the patient qualifies for manufacturer savings programs.

Active Market
This page is designed for US treatment decisions and uses US-first pricing and savings sources.
Official pricing
Verify current pricing directly on official Vyleesi pages before starting, because list pricing, self-pay offers, and eligibility terms can change.
Cash-pay reality
Official cash-pay pricing varies by pharmacy and dose. Contact multiple pharmacies or use a prescription discount service for current rates.
Insurance coverage
Commercial coverage for Bremelanotide (PT-141) varies by plan and indication. Prior authorization is commonly required.
Savings and coupons
Manufacturer savings programs may reduce out-of-pocket cost for eligible commercially insured patients.
Prior Authorization
Prior authorization is common and may require documentation of diagnosis, prior treatments, and clinical need.

Price Breakdown

List price (monthly)
~$900-$1,200/month (4-8 doses)
Average wholesale price
~$850-$1,100/month
Pharmacy acquisition estimate
~$800-$1,000/month
Typical negotiated rate
~$600-$850/month
Price per dose
~$113-$150 per 1.75 mg dose
Annual cost at list price
~$10,800-$14,400

Pharmacy Price Comparison

PharmacyPrice RangeNotes
Retail$850-$1,200/monthCash price
Specialty pharmacy$800-$1,100/monthMay offer better pricing

Insurance Coverage Landscape

Commercial plans
~30-40% for HSDD; many plans exclude sexual dysfunction
Medicare Part D
Rarely covered
Medicaid
Rarely covered
VA coverage
Case-by-case
TRICARE
Limited
Employer plan typical tier
Tier 3-4 if covered; often excluded entirely

Prior Authorization Guide

Required Documentation
  • HSDD diagnosis (acquired, generalized)
  • Premenopausal status
  • Failed counseling/therapy
  • Flibanserin trial (sometimes required)
Common Denial Reasons
  • Plan excludes sexual dysfunction drugs
  • Postmenopausal (not approved)
  • Insufficient documentation
  • Lifestyle factors not addressed
Appeal Template Points
  • FDA-approved for acquired HSDD
  • Premenopausal status confirmed
  • Psychological intervention documented
  • Medical condition affecting quality of life
Expected timeline: 1-2 weeks

Savings Programs and Patient Assistance

Vyleesi Savings Card
copay
Eligibility: Commercially insured
Savings: $0-$99/month
Income limit: None
Enrollment: simple
AMAG/Palatin program
Patient Assistance
manufacturer
Eligibility: Uninsured, ≤400% FPL
Savings: Free or reduced
Income limit: ≤400% FPL
Enrollment: moderate
Limited availability

Generic and Biosimilar Status

No generic currently available
Expected: No generic expected soon

Cost by Dose

Dose/RegimenMonthlyAnnual
1.75 mg as needed (4 doses/month)$900$10,800
1.75 mg as needed (8 doses/month)$1,200$14,400

Annual Cost Projection

Year 1
$0-$14,400
Year 2
$0-$14,400
Year 3
$0-$14,400
Assumptions
  • As-needed dosing
  • Insurance variable

Cost-Saving Strategies

  • 1.Start with 4 doses/month to assess response before increasing
  • 2.Vyleesi savings card for commercially insured
  • 3.Check if employer plan has any sexual dysfunction coverage
  • 4.Document all prior interventions for prior auth

International Price Comparison

CountryPrice RangeNotes
UKLimited availabilityNot widely marketed

Need help comparing bremelanotide (pt-141) paths?

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Trust Summary
Reviewed 2026-04-27 by PeptideScholar editorial review. This page currently cites 3 official sources.
Pricing, savings eligibility, and coverage rules can change quickly. Verify all current figures and terms directly on official brand pages before acting.

Bremelanotide (PT-141) Cost FAQ

Sources

  1. 1. Prespecified and Integrated Subgroup Analyses from the RECONNECT Phase 3 Studies of Bremelanotide.
    J Womens Health (Larchmt) • 2022
    Claim type: clinical
    View source →
  2. 2. Bremelanotide: First Approval.
    Drugs • 2019
    Claim type: review
    View source →
  3. 3. FDA Information on Bremelanotide (PT-141)
    FDA • 2026
    Claim type: regulatory
    View source →

This content is for informational purposes only and does not constitute medical advice.